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Index > Protein center > RCAN1(Gene name) > Human
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  • RCAN1 (Gene name),
  • Calcipressin-1 (Protein name ),  RCAN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    RCAN1(ADAPT78;CSP1;DSC1;DSCR1);
    Protein name:
    Calcipressin-1;
    Alternative:
    Down syndrome critical region protein 1;Adapt78;Regulator of calcineurin 1;Myocyte-enriched calcineurin-interacting protein 1(MCIP1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    252
    Sequence:
    50:
    MEDGVAGPQL | GAAAEAAEAA | EARARPGVTL | RPFAPLSGAA | EADEGGGDWS | 
    100:
    FIDCEMEEVD | LQDLPSATIA | CHLDPRVFVD | GLCRAKFESL | FRTYDKDITF | 
    150:
    QYFKSFKRVR | INFSNPFSAA | DARLQLHKTE | FLGKEMKLYF | AQTLHIGSSH | 
    200:
    LAPPNPDKQF | LISPPASPPV | GWKQVEDATP | VINYDLLYAI | SKLGPGEKYE | 
    250:
    LHAATDTTPS | VVVHVCESDQ | EKEEEEEMER | MRRPKPKIIQ | TRRPEYTPIH | 
    252:
    LS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    UniGene:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Calcipressin-1
    Cat.:
    E13874h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Calcipressin-1
    Cat.:
    E13874m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Calcipressin-1
    Cat.:
    E13874r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Calcipressin-1
    Cat.:
    E13874b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calcipressin-1
    Cat.:
    U13874b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calcipressin-1
    Cat.:
    U13874h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calcipressin-1
    Cat.:
    U13874m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Calcipressin-1
    Cat.:
    U13874r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Calcipressin-1
    Cat.:
    P13874Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Calcipressin-1
    Polyclonal Antibody for Human Calcipressin-1
    Cat.:
    P13874Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Calcipressin-1
    Cat.:
    P13874Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Calcipressin-1
    Monoclonal Antibody for Human Calcipressin-1
    Monoclonal Antibody for Human Calcipressin-1
    Monoclonal Antibody for Human Calcipressin-1
    Protein for Human Calcipressin-1
    Protein for Human Calcipressin-1
    Protein for Human Calcipressin-1
    Protein for Human Calcipressin-1

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    Precision
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    Linearity
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    References
    1. 1.
      "A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart."
      Fuentes J.-J. , Pritchard M.A. , Planas A.M. , Bosch A. , Ferrer I. , Estivill X.
      Hum. Mol. Genet.4:1935-1944(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4)
    2. 2.
      "Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene."
      Fuentes J.-J. , Pritchard M.A. , Estivill X.
      Genomics44:358-361(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 4);NUCLEOTIDE SEQUENCE [MRNA] OF 48-252 (ISOFORM 1);ALTERNATIVE SPLICING
    3. 3.
      "Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life."
      Genesca L. , Aubareda A. , Fuentes J.J. , Estivill X. , De La Luna S. , Perez-Riba M.
      Biochem. J.374:567-575(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Heart.
    4. 4.
      Hua F. , Wu J. , Zhou Y. , Zhang B. , Peng X. , Qiang B. , Yuan J. , Qiang B.
      Submitted (2001-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 9.
      "Adapt78, a calcium and oxidant-inducible RNA."
      Crawford D.R. , Leahy K.P. , Davies K.J.A.
      Submitted (1996-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-219 (ISOFORM 2)
      tissue: Mammary gland.
    9. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 38-252 (ISOFORM 1)
      tissue: Lung.
    10. 11.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 56-252 (ISOFORM 1)
    11. 12.
      "DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways."
      Fuentes J.J. , Genesca L. , Kingsbury T.J. , Cunningham K.W. , Perez-Riba M. , Estivill X. , de la Luna S.
      Hum. Mol. Genet.9:1681-1690(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    12. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAF1
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